Basel Scientists Discover Cellular 'Mini-Factories'

University of Basel researchers uncover new mechanism of protein folding in cells, potentially revolutionizing understanding of protein-related diseases and treatments.

Key Takeaways

AI

Researchers at the University of Basel have discovered that chaperone proteins organize into 'folding factories' or condensates within cells.
The protein PDIA6 is responsible for organizing these chaperone condensates.
Cells lacking these 'mini-factories' produce significantly less insulin.
The study was published in the journal Nature Cell Biology on August 11, 2025.